It includes help on how to identify when a child may be at risk and how to appropriately protect the child.
It also suggests how workers can broach the subject by offering professionals a template for how to question a child or young person at risk of FGM.
The resource pack will be launched on 26 November at a school in the London borough of Southwark.
Research carried out in 2007 that found up to 24,000 girls under the age of 15 were at risk of FGM.